Nephrology Journal Club on X: "Difelikefalin (CR845) (KORSUVA) is a peripherally restricted, selective kappa opioid receptor agonist that exerts antipruritic effects by means of activation of kappa opioid receptors on peripheral neurons
Discovery and Binding Mechanism of Pyrazoloisoquinoline-Based Novel β-Arrestin Inverse Agonists of the Kappa-Opioid Receptor | Journal of Medicinal Chemistry
Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine Dependence - ScienceDirect
Kappa Opiate Receptor - an overview | ScienceDirect Topics
Molecular mechanism of biased signaling at the kappa opioid receptor | Nature Communications
Mu Agonist Opioids and Kappa Opioids | Download Table
Kappa opioid receptor (KOR) modulation of dopamine in the cortex and... | Download Scientific Diagram
Table II from Systemic kappa opioid receptor agonists in the treatment of chronic pruritus: a literature review. | Semantic Scholar
κ-opioid receptor - Wikipedia
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor - ScienceDirect
Cara Therapeutics: Scratching An Itch Left Unscratched (NASDAQ:CARA) | Seeking Alpha
Figure 2 from Development of κ opioid receptor antagonists. | Semantic Scholar
Peripheral Kappa Opioid Receptor Signaling Takes on a Central Role | Semantic Scholar
Diverse Kappa Opioid Receptor Agonists: Relationships Between Signaling and Behavior
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Opioid Receptor | kappa, mu Opioid Receptor
An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects - ScienceDirect
Kappa Opiate Receptor Agonist - an overview | ScienceDirect Topics
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
